Northwestern University and Evanston's Only Daily News Source Since 1881

The Daily Northwestern

Northwestern University and Evanston's Only Daily News Source Since 1881

The Daily Northwestern

Northwestern University and Evanston's Only Daily News Source Since 1881

The Daily Northwestern


Advertisement
Email Newsletter

Sign up to receive our email newsletter in your inbox.



Advertisement

Advertisement
Race Against Hate: Ricky Byrdsong’s Legacy
The Week Ahead, June 17-23: Juneteenth, Summer Solstice and Pride Celebrations in Chicagoland
Evanston Environment Board drops fossil fuels divestment, recommends updates to leaf blower ordinance
Derrick Gragg appointed as Northwestern’s vice president for athletic strategy, search for new athletic director begins
Lacrosse: Northwestern’s Izzy Scane wins 2024 Honda Sport Award
District 65 School Board votes to close Dr. Bessie Rhodes School
Kathryn Hahn declares class of 2024 “worthy of celebration” in commencement address
Advertisement
Perry: A little humility goes a long way

Brew, Hou, Leung, Pandey: On being scared to tweet and the pressure to market yourself as a student journalist

June 4, 2024

Haner: A love letter to the multimedia room

June 4, 2024

Derrick Gragg appointed as Northwestern’s vice president for athletic strategy, search for new athletic director begins

Lacrosse: Northwestern’s Izzy Scane wins 2024 Honda Sport Award

June 13, 2024

Lacrosse: Northwestern’s Izzy Scane wins 2024 Tewaaraton Award

May 30, 2024

Advertisement

Campus Kitchens fills plates and hearts

NU Declassified: Prof. Barbara Butts teaches leadership through stage management

Everything Evanston: Behind the boba in downtown Evanston

As part of an international effort, Northwestern researchers started a clinical trial last month for a transplantation treatment of Type 1 diabetes

As part of an international effort, Northwestern researchers started a clinical trial last month for a transplantation treatment of Type 1 diabetes.

“It’s an attempt to come as close as we can to a cure for diabetes,” said Prof. Dixon Kaufman, a principal investigator of the study at NU.

The minimally invasive procedure implants islet cells from a donor’s pancreas into a patient with the disease. The cells produce insulin, which is absent in those with Type 1 diabetes, and help control blood sugar.

“It’s cellular replacement therapy for their failed islets,” said Kaufman, who is also the surgery vice chairman at Feinberg School of Medicine and a professor of organ transplantation.

The Phase III study, which is funded by the National Institutes of Health, will gather results from a total of 48 participants from sites across the nation and abroad, said Elyse Stuart, clinical research associate in Feinberg’s organ transplant division. This study only targets the 1 percent to 2 percent of people with Type 1 diabetes who struggle to regulate their blood sugar with conventional insulin treatments, Kaufman said.

“There’s about a million people in the United States with Type 1 diabetes, and there’s a big spectrum of severity,” he said, adding that this is the first Phase III study that has ever been done for islet transplants.

In a successful transplant, the islet cells can control blood sugar levels, although some patients still need to take small amounts of insulin, he said. The study will not test the treatment on people with Type 2 diabetes, which usually develops later in life.

NU researchers are partnered with Northwestern Memorial Hospital, which has recently built a new facility to process islet cells before transplant, Stuart said. After the study, which Kaufman estimates will be completed in about four years, scientists will try to obtain a license from the U.S. Food and Drug Administration to manufacture the cells.

More to Discover
Activate Search
Northwestern University and Evanston's Only Daily News Source Since 1881
As part of an international effort, Northwestern researchers started a clinical trial last month for a transplantation treatment of Type 1 diabetes